

Desktop Health
Synthetic biodegradable graft that remodels into native eardrum tissue for perforations
Desktop Health develops, manufactures, and markets a suite of leading 3D printing and biofabrication solutions. Specifically, their team at Greentown Labs is creating novel regenerative and biomimetic tissue grafts using biodegradable materials and additive manufacturing technologies. Desktop Health is developing PhonoGraft, a novel device for the repair of chronic eardrum perforations. Eardrum perforations occur from reasons including ear infections, traumatic injuries, and blast injuries. Currently available patient-derived and animal-derived tissue grafts lead to poor hearing and healing outcomes in patients. PhonoGraft comprises a biomimetic architecture that matches the circular and radial structure of the normal eardrum and a novel biodegradable material that remodels into tissue in the structure of the print path. PhonoGraft uses a novel biodegradable, synthetic material to reconstruct the eardrum in a biomimetic manner. PhonoGraft has shown improved outcomes in animal models compared to current standard of care graft materials.
Nicole Black
President and CEO

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